BDBM50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931

SMILES NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1

InChI Key InChIKey=SUHGRZPINGKYNV-GJZGRUSLSA-N

Data  16 KI  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50007129   

TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity was determined by measuring the ability to displace [125I]SCH-23982 from Dopamine receptor D1 in rat caudate (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity was determined by measuring the ability to displace [125I]N-(p-aminophenethyl)-spiroperidol from Dopamine receptor D2 in rat caudate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity was determined by measuring the ability to displace [125I]SCH-23982 from Dopamine receptor D1 in rat caudate (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataKi:  3nMAssay Description:Binding affinity for dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataEC50:  2nMAssay Description:Formation of cAMP on Dopamine receptor D1 in vitro in carp retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataEC50:  2.10nMAssay Description:Formation of cAMP on Dopamine receptor D1 in vitro in carp retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataEC50:  2nMAssay Description:Formation of cAMP on Dopamine receptor D1 in vitro in carp retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataEC50:  1.95nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007129((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...)
Affinity DataEC50:  2nMAssay Description:Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed